Publications sorted by year and author

2005

Bekeredjian-Ding, I. B., Wagner, M., Hornung, V., Giese, T., Schnurr, M., Endres, S., Hartmann, G., Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN. J Immunol (2005) 174, 4043.

Blankenstein, T., The role of tumor stroma in the interaction between tumor and immune system. Curr Opin Immunol (2005) 17, 180.

Bunde, T., Kirchner, A., Hoffmeister, B., Habedank, D., Hetzer, R., Cherepnev, G., Proesch, S., Reinke, P., Volk, H. D., Lehmkuhl, H., Kern, F., Protection from cytomegalovirus after transplantation is correlated with immediate early 1-specific CD8 T cells. J Exp Med (2005) 201, 1031.

Charo, J., Finkelstein, S. E., Grewal, N., Restifo, N. P., Robbins, P. F., Rosenberg, S. A., Bcl-2 overexpression enhances tumor-specific T-cell survival. Cancer Res (2005) 65, 2001.

Dauer, M., Schad, K., Herten, J., Junkmann, J., Bauer, C., Kiefl, R., Endres, S., Eigler, A., FastDC derived from human monocytes within 48 h effectively prime tumor antigen-specific cytotoxic T cells. J Immunol Methods (2005) 302, 145.

Dauer, M., Herten, J., Bauer, C., Renner, F., Schad, K., Schnurr, M., Endres, S., Eigler, A., Chemosensitization of pancreatic carcinoma cells to enhance T cell-mediated cytotoxicity induced by tumor lysate-pulsed dendritic cells. J Immunother (2005) 28, 332.

Engels, B., Noessner, E., Frankenberger, B., Blankenstein, T., Schendel, D. J., Uckert, W., Redirecting human T lymphocytes toward renal cell carcinoma specificity by retroviral transfer of T cell receptor genes. Hum Gene Ther (2005) 16, 799.

Frankenberger, B., Pohla, H., Noessner, E., Willimsky, G., Papier, B., Pezzutto, A., Kopp, J., Oberneder, R., Blankenstein, T., Schendel, D. J., Influence of CD80, interleukin-2, and interleukin-7 expression in human renal cell carcinoma on the expansion, function, and survival of tumor-specific CTLs. Clin Cancer Res (2005) 11, 1733.

Frankenberger, B., Regn, S., Geiger, C., Noessner, E., Falk, C. S., Pohla, H., Javorovic, M., Silberzahn, T., Wilde, S., Buchner, A., Siebels, M., Oberneder, R., Willimsky, G., Pezzutto, A., Blankenstein, T., Schendel, D. J., Cell-based vaccines for renal cell carcinoma: genetically-engineered tumor cells and monocyte-derived dendritic cells. World J Urol (2005) 23, 166.

Geiger, C., Regn, S., Weinzierl, A., Noessner, E., Schendel, D. J., A generic RNA-pulsed dendritic cell vaccine strategy for renal cell carcinoma. J Transl Med (2005) 3, 29.

Hammer, M. H., Meyer, S., Brestrich, G., Moosmann, A., Kern, F., Tesfa, L., Babel, N., Mittenzweig, A., Rooney, C. M., Hammerschmidt, W., Volk, H. D., Reinke, P., HLA type-independent generation of antigen-specific T cells for adoptive immunotherapy. Eur J Immunol (2005) 35, 2250.

Hartmann, G., Marschner, A., Viveros, P. R., Stahl-Hennig, C., Eisenblatter, M., Suh, Y. S., Endres, S., Tenner-Racz, K., Uberla, K., Racz, P., Steinman, R. M., Ignatius, R., CpG oligonucleotides induce strong humoral but only weak CD4+ T cell responses to protein antigens in rhesus macaques in vivo. Vaccine (2005) 23, 3310.

Hornung, V., Guenthner-Biller, M., Bourquin, C., Ablasser, A., Schlee, M., Uematsu, S., Noronha, A., Manoharan, M., Akira, S., de Fougerolles, A., Endres, S., Hartmann, G., Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med (2005) 11, 263.

Jahrsdorfer, B., Muhlenhoff, L., Blackwell, S. E., Wagner, M., Poeck, H., Hartmann, E., Jox, R., Giese, T., Emmerich, B., Endres, S., Weiner, G. J., Hartmann, G., B-cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotides. Clin Cancer Res (2005) 11, 1490.

Javorovic, M., Pohla, H., Frankenberger, B., Wolfel, T., Schendel, D. J., RNA transfer by electroporation into mature dendritic cells leading to reactivation of effector-memory cytotoxic T lymphocytes: a quantitative analysis. Mol Ther (2005) 12, 734.

Kammertoens, T., Schuler, T., Blankenstein, T., Immunotherapy: target the stroma to hit the tumor. Trends Mol Med (2005) 11, 225.

Kerkmann, M., Costa, L. T., Richter, C., Rothenfusser, S., Battiany, J., Hornung, V., Johnson, J., Englert, S., Ketterer, T., Heckl, W., Thalhammer, S., Endres, S., Hartmann, G., Spontaneous formation of nucleic acid-based nanoparticles is responsible for high interferon-alpha induction by CpG-A in plasmacytoid dendritic cells. J Biol Chem (2005) 280, 8086.

Marschner, A., Rothenfusser, S., Hornung, V., Prell, D., Krug, A., Kerkmann, M., Wellisch, D., Poeck, H., Greinacher, A., Giese, T., Endres, S., Hartmann, G., CpG ODN enhance antigen-specific NKT cell activation via plasmacytoid dendritic cells. Eur J Immunol (2005) 35, 2347.

Milani, V., Frankenberger, B., Heinz, O., Brandl, A., Ruhland, S., Issels, R. D., Noessner, E., Melanoma-associated antigen tyrosinase but not Melan-A/MART-1 expression and presentation dissociate during the heat shock response. Int Immunol (2005) 17, 257.

Roos, A. K., Pavlenko, M., Charo, J., Egevad, L., Pisa, P., Induction of PSA-specific CTLs and anti-tumor immunity by a genetic prostate cancer vaccine. Prostate (2005) 62, 217.

Schlender, J., Hornung, V., Finke, S., Gunthner-Biller, M., Marozin, S., Brzozka, K., Moghim, S., Endres, S., Hartmann, G., Conzelmann, K. K., Inhibition of toll-like receptor 7- and 9-mediated alpha/beta interferon production in human plasmacytoid dendritic cells by respiratory syncytial virus and measles virus. J Virol (2005) 79, 5507.

Willimsky, G., Blankenstein, T., Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance. Nature (2005) 437, 141.

Xue, S. A., Gao, L., Hart, D., Gillmore, R., Qasim, W., Thrasher, A., Apperley, J., Engels, B., Uckert, W., Morris, E., Stauss, H., Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene-transduced human T cells. Blood (2005) 106, 3062.

2006

Adhikary, D., Behrends, U., Moosmann, A., Witter, K., Bornkamm, G. W., Mautner, J., Control of Epstein-Barr virus infection in vitro by T helper cells specific for virion glycoproteins. J Exp Med (2006) 203, 995.

Barrantes Idel, B., Montero-Pedrazuela, A., Guadano-Ferraz, A., Obregon, M. J., Martinez de Mena, R., Gailus-Durner, V., Fuchs, H., Franz, T. J., Kalaydjiev, S., Klempt, M., Holter, S., Rathkolb, B., Reinhard, C., Morreale de Escobar, G., Bernal, J., Busch, D. H., Wurst, W., Wolf, E., Schulz, H., Shtrom, S., Greiner, E., Hrabe de Angelis, M., Westphal, H., Niehrs, C., Generation and characterization of dickkopf3 mutant mice. Mol Cell Biol (2006) 26, 2317.

Bekeredjian-Ding, I., Roth, S. I., Gilles, S., Giese, T., Ablasser, A., Hornung, V., Endres, S., Hartmann, G., T cell-independent, TLR-induced IL-12p70 production in primary human monocytes. J Immunol (2006) 176, 7438.

Bleifuss, E., Kammertoens, T., Hutloff, A., Quarcoo, D., Dorner, M., Straub, P., Uckert, W., Hildt, E., The translocation motif of hepatitis B virus improves protein vaccination. Cell Mol Life Sci (2006) 63, 627.

Bourquin, C., Schreiber, S., Beck, S., Hartmann, G., Endres, S., Immunotherapy with dendritic cells and CpG oligonucleotides can be combined with chemotherapy without loss of efficacy in a mouse model of colon cancer. Int J Cancer (2006) 118, 2790.

Cohen, C. D., Klingenhoff, A., Boucherot, A., Nitsche, A., Henger, A., Brunner, B., Schmid, H., Merkle, M., Saleem, M. A., Koller, K. P., Werner, T., Grone, H. J., Nelson, P. J., Kretzler, M., Comparative promoter analysis allows de novo identification of specialized cell junction-associated proteins. Proc Natl Acad Sci U S A (2006) 103, 5682.

Dauer, M., Schad, K., Junkmann, J., Bauer, C., Herten, J., Kiefl, R., Schnurr, M., Endres, S., Eigler, A., IFN-alpha promotes definitive maturation of dendritic cells generated by short-term culture of monocytes with GM-CSF and IL-4. J Leukoc Biol (2006) 80, 278.

Djafarzadeh, R., Noessner, E., Engelmann, H., Schendel, D. J., Notohamiprodjo, M., von Luettichau, I., Nelson, P. J., GPI-anchored TIMP-1 treatment renders renal cell carcinoma sensitive to FAS-meditated killing. Oncogene (2006) 25, 1496.

Eigenbrod, S., Derwand, R., Jakl, V., Endres, S., Eigler, A., Sphingosine kinase and sphingosine-1-phosphate regulate migration, endocytosis and apoptosis of dendritic cells. Immunol Invest (2006) 35, 149.

Endl, J., Rosinger, S., Schwarz, B., Friedrich, S. O., Rothe, G., Karges, W., Schlosser, M., Eiermann, T., Schendel, D. J., Boehm, B. O., Coexpression of CD25 and OX40 (CD134) receptors delineates autoreactive T-cells in type 1 diabetes. Diabetes (2006) 55, 50.

Feederle, R., Neuhierl, B., Baldwin, G., Bannert, H., Hub, B., Mautner, J., Behrends, U., Delecluse, H. J., Epstein-Barr virus BNRF1 protein allows efficient transfer from the endosomal compartment to the nucleus of primary B lymphocytes. J Virol (2006) 80, 9435.

Gvozdenovic, B. S., Zugic, V., Lapcevic, M., Vukovic, M., Milosevic, S., Plavsic, S., Orlovic, S. Z., [Relationship between respiratory symptoms and satisfaction with inhaled asthma medication]. Srp Arh Celok Lek (2006) 134, 498.

Hammer, M. H., Brestrich, G., Andree, H., Engelmann, E., Rosenberger, C., Tillmann, H., Zwinger, S., Babel, N., Nickel, P., Volk, H. D., Reinke, P., HLA type-independent method to monitor polyoma BK virus-specific CD4 and CD8 T-cell immunity. Am J Transplant (2006) 6, 625.

Hartmann, E., Graefe, H., Hopert, A., Pries, R., Rothenfusser, S., Poeck, H., Mack, B., Endres, S., Hartmann, G., Wollenberg, B., Analysis of plasmacytoid and myeloid dendritic cells in nasal epithelium. Clin Vaccine Immunol (2006) 13, 1278.

Hettich, E., Janz, A., Zeidler, R., Pich, D., Hellebrand, E., Weissflog, B., Moosmann, A., Hammerschmidt, W., Genetic design of an optimized packaging cell line for gene vectors transducing human B cells. Gene Ther (2006) 13, 844.

Hornung, V., Ellegast, J., Kim, S., Brzozka, K., Jung, A., Kato, H., Poeck, H., Akira, S., Conzelmann, K. K., Schlee, M., Endres, S., Hartmann, G., 5'-Triphosphate RNA is the ligand for RIG-I. Science (2006) 314, 994.

Huster, K. M., Koffler, M., Stemberger, C., Schiemann, M., Wagner, H., Busch, D. H., Unidirectional development of CD8+ central memory T cells into protective Listeria-specific effector memory T cells. Eur J Immunol (2006) 36, 1453.

Kerkmann, M., Lochmann, D., Weyermann, J., Marschner, A., Poeck, H., Wagner, M., Battiany, J., Zimmer, A., Endres, S., Hartmann, G., Immunostimulatory properties of CpG-oligonucleotides are enhanced by the use of protamine nanoparticles. Oligonucleotides (2006) 16, 313.

Lang, S., Picu, A., Hofmann, T., Andratschke, M., Mack, B., Moosmann, A., Gires, O., Tiwari, S., Zeidler, R., COX-inhibitors relieve the immunosuppressive effect of tumor cells and improve functions of immune effectors. Int J Immunopathol Pharmacol (2006) 19, 409.

Massberg, S., Konrad, I., Schurzinger, K., Lorenz, M., Schneider, S., Zohlnhoefer, D., Hoppe, K., Schiemann, M., Kennerknecht, E., Sauer, S., Schulz, C., Kerstan, S., Rudelius, M., Seidl, S., Sorge, F., Langer, H., Peluso, M., Goyal, P., Vestweber, D., Emambokus, N. R., Busch, D. H., Frampton, J., Gawaz, M., Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo. J Exp Med (2006) 203, 1221.

Milani, V., Noessner, E., Effects of thermal stress on tumor antigenicity and recognition by immune effector cells. Cancer Immunol Immunother (2006) 55, 312.

Milosevic, S., Behrends, U., Adhikary, D., Mautner, J., Identification of major histocompatibility complex class II-restricted antigens and epitopes of the Epstein-Barr virus by a novel bacterial expression cloning approach. J Virol (2006) 80, 10357.

Neuenhahn, M., Kerksiek, K. M., Nauerth, M., Suhre, M. H., Schiemann, M., Gebhardt, F. E., Stemberger, C., Panthel, K., Schroder, S., Chakraborty, T., Jung, S., Hochrein, H., Russmann, H., Brocker, T., Busch, D. H., CD8alpha+ dendritic cells are required for efficient entry of Listeria monocytogenes into the spleen. Immunity (2006) 25, 619.

Noessner, E., Thermal stress-related modulation of tumor cell physiology and immune responses. Cancer Immunol Immunother (2006) 55, 289.

Notohamiprodjo, M., Djafarzadeh, R., Mojaat, A., von Luttichau, I., Grone, H. J., Nelson, P. J., Generation of GPI-linked CCL5 based chemokine receptor antagonists for the suppression of acute vascular damage during allograft transplantation. Protein Eng Des Sel (2006) 19, 27.

Osterloh, P., Linkemann, K., Tenzer, S., Rammensee, H. G., Radsak, M. P., Busch, D. H., Schild, H., Proteasomes shape the repertoire of T cells participating in antigen-specific immune responses. Proc Natl Acad Sci U S A (2006) 103, 5042.

Panthel, K., Meinel, K. M., Sevil Domenech, V. E., Geginat, G., Linkemann, K., Busch, D. H., Russmann, H., Prophylactic anti-tumor immunity against a murine fibrosarcoma triggered by the Salmonella type III secretion system. Microbes Infect (2006) 8, 2539.

Savoldo, B., Goss, J. A., Hammer, M. M., Zhang, L., Lopez, T., Gee, A. P., Lin, Y. F., Quiros-Tejeira, R. E., Reinke, P., Schubert, S., Gottschalk, S., Finegold, M. J., Brenner, M. K., Rooney, C. M., Heslop, H. E., Treatment of solid organ transplant recipients with autologous Epstein Barr virus-specific cytotoxic T lymphocytes (CTLs). Blood (2006) 108, 2942.

Schleypen, J. S., Baur, N., Kammerer, R., Nelson, P. J., Rohrmann, K., Grone, E. F., Hohenfellner, M., Haferkamp, A., Pohla, H., Schendel, D. J., Falk, C. S., Noessner, E., Cytotoxic markers and frequency predict functional capacity of natural killer cells infiltrating renal cell carcinoma. Clin Cancer Res (2006) 12, 718.

Schmid, H., Boucherot, A., Yasuda, Y., Henger, A., Brunner, B., Eichinger, F., Nitsche, A., Kiss, E., Bleich, M., Grone, H. J., Nelson, P. J., Schlondorff, D., Cohen, C. D., Kretzler, M., Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy. Diabetes (2006) 55, 2993.

Segerer, S., Henger, A., Schmid, H., Kretzler, M., Draganovici, D., Brandt, U., Noessner, E., Nelson, P. J., Kerjaschki, D., Schlondorff, D., Regele, H., Expression of the chemokine receptor CXCR1 in human glomerular diseases. Kidney Int (2006) 69, 1765.

Sommermeyer, D., Neudorfer, J., Weinhold, M., Leisegang, M., Engels, B., Noessner, E., Heemskerk, M. H., Charo, J., Schendel, D. J., Blankenstein, T., Bernhard, H., Uckert, W., Designer T cells by T cell receptor replacement. Eur J Immunol (2006) 36, 3052.

Volk, H. D., Sawitzki, B., Kern, F., Hoflich, C., Sabat, R., Reinke, P., Immunomodulatory therapies: challenges of individualized therapy strategies. Ernst Schering Found Symp Proc (2006), 59.

von Geldern, M., Simm, B., Braun, M., Weiss, E. H., Schendel, D. J., Falk, C. S., TCR-independent cytokine stimulation induces non-MHC-restricted T cell activity and is negatively regulated by HLA class I. Eur J Immunol (2006) 36, 2347.

von Luettichau, I., Nathrath, M., Burdach, S., Huss, R., Segerer, S., Nelson, P. J., Mononuclear infiltrates in osteosarcoma and chemokine receptor expression. Clin Cancer Res (2006) 12, 5253.

Wingender, G., Garbi, N., Schumak, B., Jungerkes, F., Endl, E., von Bubnoff, D., Steitz, J., Striegler, J., Moldenhauer, G., Tuting, T., Heit, A., Huster, K. M., Takikawa, O., Akira, S., Busch, D. H., Wagner, H., Hammerling, G. J., Knolle, P. A., Limmer, A., Systemic application of CpG-rich DNA suppresses adaptive T cell immunity via induction of IDO. Eur J Immunol (2006) 36, 12.

2007 

Adhikary, D., Behrends, U., Boerschmann, H., Pfunder, A., Burdach, S., Moosmann, A., Witter, K., Bornkamm, G. W., Mautner, J., Immunodominance of lytic cycle antigens in epstein-barr virus-specific CD4+ T cell preparations for therapy. PLoS ONE (2007) 2, e583.

Agger, R., Petersen, M. S., Petersen, C. C., Hansen, S. B., Stodkilde-Jorgensen, H., Skands, U., Blankenstein, T., Andersen, T. E., Hulgaard, E. F., Jorgensen, J. T., Marqversen, J., Gundersen, H. J., Hokland, M. E., T cell homing to tumors detected by 3D-coordinated positron emission tomography and magnetic resonance imaging. J Immunother (2007) 30, 29.

Allgeier, T., Garhammer, S., Nossner, E., Wahl, U., Kronenberger, K., Dreyling, M., Hallek, M., Mocikat, R., Dendritic cell-based immunogens for B-cell chronic lymphocytic leukemia. Cancer Lett (2007) 245, 275.

Bauer, C., Loher, F., Dauer, M., Mayer, C., Lehr, H. A., Schonharting, M., Hallwachs, R., Endres, S., Eigler, A., The ICE inhibitor pralnacasan prevents DSS-induced colitis in C57BL/6 mice and suppresses IP-10 mRNA but not TNF-alpha mRNA expression. Dig Dis Sci (2007) 52, 1642.

Bauer, C., Bauernfeind, F., Sterzik, A., Orban, M., Schnurr, M., Lehr, H. A., Endres, S., Eigler, A., Dauer, M., Dendritic cell-based vaccination combined with gemcitabine increases survival in a murine pancreatic carcinoma model. Gut (2007) 56, 1275.

Bekeredjian-Ding, I., Inamura, S., Giese, T., Moll, H., Endres, S., Sing, A., Zahringer, U., Hartmann, G., Staphylococcus aureus protein A triggers T cell-independent B cell proliferation by sensitizing B cells for TLR2 ligands. J Immunol (2007) 178, 2803.

Bendz, H., Ruhland, S. C., Pandya, M. J., Hainzl, O., Riegelsberger, S., Brauchle, C., Mayer, M. P., Buchner, J., Issels, R. D., Noessner, E., Human heat shock protein 70 enhances tumor antigen presentation through complex formation and intracellular antigen delivery without innate immune signaling. J Biol Chem (2007) 282, 31688.

Blankenstein, T., Do autochthonous tumors interfere with effector T cell responses? Semin Cancer Biol (2007) 17, 267.

Bourquin, C., Schmidt, L., Hornung, V., Wurzenberger, C., Anz, D., Sandholzer, N., Schreiber, S., Voelkl, A., Hartmann, G., Endres, S., Immunostimulatory RNA oligonucleotides trigger an antigen-specific cytotoxic T-cell and IgG2a response. Blood (2007) 109, 2953.

Brill, T. H., Kubler, H. R., von Randenborgh, H., Fend, F., Pohla, H., Breul, J., Hartung, R., Paul, R., Schendel, D. J., Gansbacher, B., Allogeneic retrovirally transduced, IL-2- and IFN-gamma-secreting cancer cell vaccine in patients with hormone refractory prostate cancer--a phase I clinical trial. J Gene Med (2007) 9, 547.

Cayeux, S., Bukarica, B., Buschow, C., Charo, J., Bunse, M., Dorken, B., Blankenstein, T., In vivo splenic CD11c cells downregulate CD4 T-cell response thereby decreasing systemic immunity to gene-modified tumour cell vaccine. Gene Ther (2007) 14, 1481.

Charo, J., Robbins, P. F., Contrasting effects of FLIPL overexpression in human T cells on activation-induced cell death and cytokine production. J Leukoc Biol (2007) 81, 1297.

Conrad, C., Gupta, R., Mohan, H., Niess, H., Bruns, C. J., Kopp, R., von Luettichau, I., Guba, M., Heeschen, C., Jauch, K. W., Huss, R., Nelson, P. J., Genetically engineered stem cells for therapeutic gene delivery. Curr Gene Ther (2007) 7, 249.

Cosma, A., Nagaraj, R., Staib, C., Diemer, C., Wopfner, F., Schatzl, H., Busch, D. H., Sutter, G., Goebel, F. D., Erfle, V., Evaluation of modified vaccinia virus Ankara as an alternative vaccine against smallpox in chronically HIV type 1-infected individuals undergoing HAART. AIDS Res Hum Retroviruses (2007) 23, 782.

Engels, B., Uckert, W., Redirecting T lymphocyte specificity by T cell receptor gene transfer--a new era for immunotherapy. Mol Aspects Med (2007) 28, 115.

Ewing, P., Hildebrandt, G. C., Planke, S., Andreesen, R., Holler, E., Gerbitz, A., Cobalt protoporphyrine IX-mediated heme oxygenase-I induction alters the inflammatory cytokine response, but not antigen presentation after experimental allogeneic bone marrow transplantation. Int J Mol Med (2007) 20, 301.

Frankenberger, B., Noessner, E., Schendel, D. J., Immune suppression in renal cell carcinoma. Semin Cancer Biol (2007) 17, 330.

Gamrekelashvili, J., Kruger, C., von Wasielewski, R., Hoffmann, M., Huster, K. M., Busch, D. H., Manns, M. P., Korangy, F., Greten, T. F., Necrotic tumor cell death in vivo impairs tumor-specific immune responses. J Immunol (2007) 178, 1573.

Grau, S. J., Trillsch, F., Herms, J., Thon, N., Nelson, P. J., Tonn, J. C., Goldbrunner, R., Expression of VEGFR3 in glioma endothelium correlates with tumor grade. J Neurooncol (2007) 82, 141.

Greten, F. R., Arkan, M. C., Bollrath, J., Hsu, L. C., Goode, J., Miething, C., Goktuna, S. I., Neuenhahn, M., Fierer, J., Paxian, S., Van Rooijen, N., Xu, Y., O'Cain, T., Jaffee, B. B., Busch, D. H., Duyster, J., Schmid, R. M., Eckmann, L., Karin, M., NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell (2007) 130, 918.

Hamm, S., Heit, A., Koffler, M., Huster, K. M., Akira, S., Busch, D. H., Wagner, H., Bauer, S., Immunostimulatory RNA is a potent inducer of antigen-specific cytotoxic and humoral immune response in vivo. Int Immunol (2007) 19, 297.

Hammer, M. H., Brestrich, G., Mittenzweig, A., Roemhild, A., Zwinger, S., Subklewe, M., Beier, C., Kurtz, A., Babel, N., Volk, H. D., Reinke, P., Generation of EBV-specific T cells for adoptive immunotherapy: a novel protocol using formalin-fixed stimulator cells to increase biosafety. J Immunother (2007) 30, 817.

Heit, A., Schmitz, F., Haas, T., Busch, D. H., Wagner, H., Antigen co-encapsulated with adjuvants efficiently drive protective T cell immunity. Eur J Immunol (2007) 37, 2063.

Kastenmuller, W., Gasteiger, G., Gronau, J. H., Baier, R., Ljapoci, R., Busch, D. H., Drexler, I., Cross-competition of CD8+ T cells shapes the immunodominance hierarchy during boost vaccination. J Exp Med (2007) 204, 2187.

Khalil, P. N., Weiler, V., Nelson, P. J., Khalil, M. N., Moosmann, S., Mutschler, W. E., Siebeck, M., Huss, R., Nonmyeloablative stem cell therapy enhances microcirculation and tissue regeneration in murine inflammatory bowel disease. Gastroenterology (2007) 132, 944.

Krause, M., Schmitz, M., Noessner, E., Skrablin, P. S., Wehner, R., Rieber, E. P., Baumann, M., Adoptive transfer of cytotoxic T-cells for treatment of residual disease after irradiation. Int J Radiat Biol (2007) 83, 827.

Lang, S., Tiwari, S., Andratschke, M., Loehr, I., Lauffer, L., Bergmann, C., Mack, B., Lebeau, A., Moosmann, A., Whiteside, T. L., Zeidler, R., Immune restoration in head and neck cancer patients after in vivo COX-2 inhibition. Cancer Immunol Immunother (2007) 56, 1645.

Letsch, A., Knoedler, M., Na, I. K., Kern, F., Asemissen, A. M., Keilholz, U., Loesch, M., Thiel, E., Volk, H. D., Scheibenbogen, C., CMV-specific central memory T cells reside in bone marrow. Eur J Immunol (2007) 37, 3063.

Li, Z., Pradera, F., Kammertoens, T., Li, B., Liu, S., Qin, Z., Cross-talk between T cells and innate immune cells is crucial for IFN-gamma-dependent tumor rejection. J Immunol (2007) 179, 1568.

McNicol, A. M., Bendle, G., Holler, A., Matjeka, T., Dalton, E., Rettig, L., Zamoyska, R., Uckert, W., Xue, S. A., Stauss, H. J., CD8alpha/alpha homodimers fail to function as co-receptor for a CD8-dependent TCR. Eur J Immunol (2007) 37, 1634.

Nassenstein, C., Kammertoens, T., Veres, T. Z., Uckert, W., Spies, E., Fuchs, B., Krug, N., Braun, A., Neuroimmune crosstalk in asthma: dual role of the neurotrophin receptor p75NTR. J Allergy Clin Immunol (2007) 120, 1089.

Neudorfer, J., Schmidt, B., Huster, K. M., Anderl, F., Schiemann, M., Holzapfel, G., Schmidt, T., Germeroth, L., Wagner, H., Peschel, C., Busch, D. H., Bernhard, H., Reversible HLA multimers (Streptamers) for the isolation of human cytotoxic T lymphocytes functionally active against tumor- and virus-derived antigens. J Immunol Methods (2007) 320, 119.

Reuss, S., Biese, P., Cosset, F. L., Takeuchi, Y., Uckert, W., Suspension packaging cell lines for the simplified generation of T-cell receptor encoding retrovirus vector particles. Gene Ther (2007) 14, 595.

Rubio-Aliaga, I., Soewarto, D., Wagner, S., Klaften, M., Fuchs, H., Kalaydjiev, S., Busch, D. H., Klempt, M., Rathkolb, B., Wolf, E., Abe, K., Zeiser, S., Przemeck, G. K., Beckers, J., de Angelis, M. H., A genetic screen for modifiers of the delta1-dependent notch signaling function in the mouse. Genetics (2007) 175, 1451.

Schulz, C., Schafer, A., Stolla, M., Kerstan, S., Lorenz, M., von Bruhl, M. L., Schiemann, M., Bauersachs, J., Gloe, T., Busch, D. H., Gawaz, M., Massberg, S., Chemokine fractalkine mediates leukocyte recruitment to inflammatory endothelial cells in flowing whole blood: a critical role for P-selectin expressed on activated platelets. Circulation (2007) 116, 764.

Schuster, I. G., Busch, D. H., Eppinger, E., Kremmer, E., Milosevic, S., Hennard, C., Kuttler, C., Ellwart, J. W., Frankenberger, B., Nossner, E., Salat, C., Bogner, C., Borkhardt, A., Kolb, H. J., Krackhardt, A. M., Allorestricted T cells with specificity for the FMNL1-derived peptide PP2 have potent antitumor activity against hematologic and other malignancies. Blood (2007) 110, 2931.

Segerer, S., Djafarzadeh, R., Grone, H. J., Weingart, C., Kerjaschki, D., Weber, C., Kungl, A. J., Regele, H., Proudfoot, A. E., Nelson, P. J., Selective binding and presentation of CCL5 by discrete tissue microenvironments during renal inflammation. J Am Soc Nephrol (2007) 18, 1835.

Stemberger, C., Huster, K. M., Koffler, M., Anderl, F., Schiemann, M., Wagner, H., Busch, D. H., A single naive CD8+ T cell precursor can develop into diverse effector and memory subsets. Immunity (2007) 27, 985.

Weinhold, M., Sommermeyer, D., Uckert, W., Blankenstein, T., Dual T cell receptor expressing CD8+ T cells with tumor- and self-specificity can inhibit tumor growth without causing severe autoimmunity. J Immunol (2007) 179, 5534.

Wiethe, C., Schiemann, M., Busch, D., Haeberle, L., Kopf, M., Schuler, G., Lutz, M. B., Interdependency of MHC class II/self-peptide and CD1d/self-glycolipid presentation by TNF-matured dendritic cells for protection from autoimmunity. J Immunol (2007) 178, 4908.

Willimsky, G., Blankenstein, T., The adaptive immune response to sporadic cancer. Immunol Rev (2007) 220, 102.

Witter, K., Mautner, J., Albert, T., Zahn, R., Kauke, T., HLA-DQB1*0319, a novel HLA-DQB1 allele, shows strong haplotype association to HLA-DRB1*1102. Tissue Antigens (2007) 70, 73.

Zentz, C., Wiesner, M., Man, S., Frankenberger, B., Wollenberg, B., Hillemanns, P., Zeidler, R., Hammerschmidt, W., Moosmann, A., Activated B cells mediate efficient expansion of rare antigen-specific T cells. Hum Immunol (2007) 68, 75.

2008

Abe, K., Wechs, S., Kalaydjiev, S., Franz, T. J., Busch, D. H., Fuchs, H., Soewarto, D., Behrendt, H., Wagner, S., Jakob, T., Hrabe de Angelis, M., Novel lymphocyte-independent mechanisms to initiate inflammatory arthritis via bone marrow-derived cells of Ali18 mutant mice. Rheumatology (Oxford) (2008) 47, 292.

Adhikary, D., Behrends, U., Feederle, R., Delecluse, H. J., Mautner, J., Standardized and highly efficient expansion of Epstein-Barr virus-specific CD4+ T cells by using virus-like particles. J Virol (2008) 82, 3903.

Allam, R., Pawar, R. D., Kulkarni, O. P., Hornung, V., Hartmann, G., Segerer, S., Akira, S., Endres, S., Anders, H. J., Viral 5'-triphosphate RNA and non-CpG DNA aggravate autoimmunity and lupus nephritis via distinct TLR-independent immune responses. Eur J Immunol (2008) 38, 3487.

Bendz, H., Marincek, B. C., Momburg, F., Ellwart, J. W., Issels, R. D., Nelson, P. J., Noessner, E., Calcium signaling in dendritic cells by human or mycobacterial Hsp70 is caused by contamination and is not required for Hsp70-mediated enhancement of cross-presentation. J Biol Chem (2008) 283, 26477.

Bernhard, H., Neudorfer, J., Gebhard, K., Conrad, H., Hermann, C., Nahrig, J., Fend, F., Weber, W., Busch, D. H., Peschel, C., Adoptive transfer of autologous, HER2-specific, cytotoxic T lymphocytes for the treatment of HER2-overexpressing breast cancer. Cancer Immunol Immunother (2008) 57, 271.

Bleifuss, E., Bendz, H., Sirch, B., Thompson, S., Brandl, A., Milani, V., Graner, M. W., Drexler, I., Kuppner, M., Katsanis, E., Noessner, E., Issels, R. D., Differential capacity of chaperone-rich lysates in cross-presenting human endogenous and exogenous melanoma differentiation antigens. Int J Hyperthermia (2008) 24, 623.

Bourquin, C., van der Haar, M. E., Anz, D., Sandholzer, N., Neumaier, I., Endres, S., Skerra, A., Schwab, M. E., Linington, C., DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune encephalomyelitis. Eur J Pharmacol (2008) 588, 99.

Bourquin, C., Anz, D., Zwiorek, K., Lanz, A. L., Fuchs, S., Weigel, S., Wurzenberger, C., von der Borch, P., Golic, M., Moder, S., Winter, G., Coester, C., Endres, S., Targeting CpG oligonucleotides to the lymph node by nanoparticles elicits efficient antitumoral immunity. J Immunol (2008) 181, 2990.

Brunner, S., Huber, B. C., Fischer, R., Groebner, M., Hacker, M., David, R., Zaruba, M. M., Vallaster, M., Rischpler, C., Wilke, A., Gerbitz, A., Franz, W. M., G-CSF treatment after myocardial infarction: impact on bone marrow-derived vs cardiac progenitor cells. Exp Hematol (2008) 36, 695.

Conrad, H., Gebhard, K., Kronig, H., Neudorfer, J., Busch, D. H., Peschel, C., Bernhard, H., CTLs directed against HER2 specifically cross-react with HER3 and HER4. J Immunol (2008) 180, 8135.

Conrad, C., Zeindl-Eberhart, E., Moosmann, S., Nelson, P. J., Bruns, C. J., Huss, R., Alkaline phosphatase, glutathione-S-transferase-P, and cofilin-1 distinguish multipotent mesenchymal stromal cell lines derived from the bone marrow versus peripheral blood. Stem Cells Dev (2008) 17, 23.

Dauer, M., Lam, V., Arnold, H., Junkmann, J., Kiefl, R., Bauer, C., Schnurr, M., Endres, S., Eigler, A., Combined use of toll-like receptor agonists and prostaglandin E(2) in the FastDC model: rapid generation of human monocyte-derived dendritic cells capable of migration and IL-12p70 production. J Immunol Methods (2008) 337, 97.

Delecluse, H. J., Feederle, R., Behrends, U., Mautner, J., Contribution of viral recombinants to the study of the immune response against the Epstein-Barr virus. Semin Cancer Biol (2008) 18, 409.

Ebelt, K., Babaryka, G., Figel, A. M., Pohla, H., Buchner, A., Stief, C. G., Eisenmenger, W., Kirchner, T., Schendel, D. J., Noessner, E., Dominance of CD4+ lymphocytic infiltrates with disturbed effector cell characteristics in the tumor microenvironment of prostate carcinoma. Prostate (2008) 68, 1.

Frenzel, L. P., Abdullah, Z., Kriegeskorte, A. K., Dieterich, R., Lange, N., Busch, D. H., Kronke, M., Utermohlen, O., Hescheler, J., Saric, T., Role of NKG2D-ligands and ICAM-1 in NK cell-mediated Lysis of Murine Embryonic Stem Cells and Embryonic Stem Cell-derived Cardiomyocytes. Stem Cells (2008).

Fuhrmann, S., Streitz, M., Reinke, P., Volk, H. D., Kern, F., T cell response to the cytomegalovirus major capsid protein (UL86) is dominated by helper cells with a large polyfunctional component and diverse epitope recognition. J Infect Dis (2008) 197, 1455.

Gerbitz, A., Hillemanns, P., Schmid, C., Wilke, A., Jayaraman, R., Kolb, H. J., Eissner, G., Holler, E., Influence of polymorphism within the heme oxygenase-I promoter on overall survival and transplantation-related mortality after allogeneic stem cell transplantation. Biol Blood Marrow Transplant (2008) 14, 1180.

Grau, S. J., Trillsch, F., von Luttichau, I., Nelson, P. J., Herms, J., Tonn, J. C., Goldbrunner, R. H., Lymphatic phenotype of tumour vessels in malignant gliomas. Neuropathol Appl Neurobiol (2008) 34, 675.

Heit, A., Gebhardt, F., Lahl, K., Neuenhahn, M., Schmitz, F., Anderl, F., Wagner, H., Sparwasser, T., Busch, D. H., Kastenmuller, K., Circumvention of regulatory CD4(+) T cell activity during cross-priming strongly enhances T cell-mediated immunity. Eur J Immunol (2008) 38, 1585.

Javorovic, M., Wilde, S., Zobywalski, A., Noessner, E., Lennerz, V., Wolfel, T., Schendel, D. J., Inhibitory effect of RNA pool complexity on stimulatory capacity of RNA-pulsed dendritic cells. J Immunother (2008) 31, 52.

Kieback, E., Charo, J., Sommermeyer, D., Blankenstein, T., Uckert, W., A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer. Proc Natl Acad Sci U S A (2008) 105, 623.

Kirchner, A., Hoffmeister, B., Cherepnev, G. G., Fuhrmann, S., Streitz, M., Lachmann, R., Bunde, T., Meij, P., Schonemann, C., Hetzer, R., Lehmkuhl, H. B., Volkmer-Engert, R., Volk, H. D., Gratama, J. W., Kern, F., Dissection of the CMV specific T-cell response is required for optimized cardiac transplant monitoring. J Med Virol (2008) 80, 1604.

Kronenberger, K., Nossner, E., Frankenberger, B., Wahl, U., Dreyling, M., Hallek, M., Mocikat, R., A polyvalent cellular vaccine induces T-cell responses against specific self-antigens overexpressed in chronic lymphocytic B-cell leukemia. J Immunother (2008) 31, 723.

Kruschinski, A., Moosmann, A., Poschke, I., Norell, H., Chmielewski, M., Seliger, B., Kiessling, R., Blankenstein, T., Abken, H., Charo, J., Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas. Proc Natl Acad Sci U S A (2008) 105, 17481.

Kuppner, M. C., Bleifuss, E., Noessner, E., Mocikat, R., Hesler, C., Mayerhofer, C., Issels, R. D., Differential effects of ifosfamide on dendritic cell-mediated stimulation of T cell interleukin-2 production, natural killer cell cytotoxicity and interferon-gamma production. Clin Exp Immunol (2008) 153, 429.

Kuprash, D. V., Qin, Z., Ito, D., Grivennikov, S. I., Abe, K., Drutskaya, L. N., Blankenstein, T., Nedospasov, S. A., Ablation of TNF or lymphotoxin signaling and the frequency of spontaneous tumors in p53-deficient mice. Cancer Lett (2008) 268, 70.

Leisegang, M., Engels, B., Meyerhuber, P., Kieback, E., Sommermeyer, D., Xue, S. A., Reuss, S., Stauss, H., Uckert, W., Enhanced functionality of T cell receptor-redirected T cells is defined by the transgene cassette. J Mol Med (2008) 86, 573.

Li, L., Willimsky, G., Seitz, S., Xu, Y., Li, Y., Schwarz, L. E., Schlag, P. M., Blankenstein, T., SV40 large T antigen-transformed human primary normal and cancerous mammary epithelial cells are phenotypically similar but can be distinguished in 3D culture with selection medium. Int J Cancer (2008) 123, 1516.

Lochner, M., Kastenmuller, K., Neuenhahn, M., Weighardt, H., Busch, D. H., Reindl, W., Forster, I., Decreased susceptibility of mice to infection with Listeria monocytogenes in the absence of interleukin-18. Infect Immun (2008) 76, 3881.

Luking, C., Kronenberger, K., Frankenberger, B., Nossner, E., Rocken, M., Mocikat, R., Antitumor effector functions of T cells are dependent on in vivo priming and restricted T-cell receptor expression. Int J Cancer (2008) 122, 2280.

Meier, S., Stark, R., Frentsch, M., Thiel, A., The influence of different stimulation conditions on the assessment of antigen-induced CD154 expression on CD4+ T cells. Cytometry A (2008) 73, 1035.

Poeck, H., Besch, R., Maihoefer, C., Renn, M., Tormo, D., Morskaya, S. S., Kirschnek, S., Gaffal, E., Landsberg, J., Hellmuth, J., Schmidt, A., Anz, D., Bscheider, M., Schwerd, T., Berking, C., Bourquin, C., Kalinke, U., Kremmer, E., Kato, H., Akira, S., Meyers, R., Hacker, G., Neuenhahn, M., Busch, D., Ruland, J., Rothenfusser, S., Prinz, M., Hornung, V., Endres, S., Tuting, T., Hartmann, G., 5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma. Nat Med (2008) 14, 1256.

Riedel, A., Nimmerjahn, F., Burdach, S., Behrends, U., Bornkamm, G. W., Mautner, J., Endogenous presentation of a nuclear antigen on MHC class II by autophagy in the absence of CRM1-mediated nuclear export. Eur J Immunol (2008) 38, 2090.

Sakowicz-Burkiewicz, M., Nishanth, G., Helmuth, U., Drogemuller, K., Busch, D. H., Utermohlen, O., Naumann, M., Deckert, M., Schluter, D., Protein kinase C-theta critically regulates the proliferation and survival of pathogen-specific T cells in murine listeriosis. J Immunol (2008) 180, 5601.

Sawitzki, B., Reinke, P., Volk, H. D., Wood, K., Turka, L. A., Autoimmunity and transplantation: a meeting at the crossroads in Berlin. Nat Immunol (2008) 9, 447.

Schlosser, E., Mueller, M., Fischer, S., Basta, S., Busch, D. H., Gander, B., Groettrup, M., TLR ligands and antigen need to be coencapsulated into the same biodegradable microsphere for the generation of potent cytotoxic T lymphocyte responses. Vaccine (2008) 26, 1626.

Schmid, C., Schleuning, M., Hentrich, M., Markl, G. E., Gerbitz, A., Tischer, J., Ledderose, G., Oruzio, D., Hiddemann, W., Kolb, H. J., High antileukemic efficacy of an intermediate intensity conditioning regimen for allogeneic stem cell transplantation in patients with high-risk acute myeloid leukemia in first complete remission. Bone Marrow Transplant (2008) 41, 721.

Segerer, S., Heller, F., Lindenmeyer, M. T., Schmid, H., Cohen, C. D., Draganovici, D., Mandelbaum, J., Nelson, P. J., Grone, H. J., Grone, E. F., Figel, A. M., Nossner, E., Schlondorff, D., Compartment specific expression of dendritic cell markers in human glomerulonephritis. Kidney Int (2008) 74, 37.

Sewald, X., Gebert-Vogl, B., Prassl, S., Barwig, I., Weiss, E., Fabbri, M., Osicka, R., Schiemann, M., Busch, D. H., Semmrich, M., Holzmann, B., Sebo, P., Haas, R., Integrin subunit CD18 Is the T-lymphocyte receptor for the Helicobacter pylori vacuolating cytotoxin. Cell Host Microbe (2008) 3, 20.

Shin, A., Toy, T., Rothenfusser, S., Robson, N., Vorac, J., Dauer, M., Stuplich, M., Endres, S., Cebon, J., Maraskovsky, E., Schnurr, M., P2Y receptor signaling regulates phenotype and IFN-alpha secretion of human plasmacytoid dendritic cells. Blood (2008) 111, 3062.

von Luettichau, I., Segerer, S., Wechselberger, A., Notohamiprodjo, M., Nathrath, M., Kremer, M., Henger, A., Djafarzadeh, R., Burdach, S., Huss, R., Nelson, P. J., A complex pattern of chemokine receptor expression is seen in osteosarcoma. BMC Cancer (2008) 8, 23.

Walzlein, J. H., Synowitz, M., Engels, B., Markovic, D. S., Gabrusiewicz, K., Nikolaev, E., Yoshikawa, K., Kaminska, B., Kempermann, G., Uckert, W., Kaczmarek, L., Kettenmann, H., Glass, R., The antitumorigenic response of neural precursors depends on subventricular proliferation and age. Stem Cells (2008) 26, 2945.

Weingart, C., Nelson, P. J., Kramer, B. K., Mack, M., Dose dependent effects of platelet derived chondroitinsulfate A on the binding of CCL5 to endothelial cells. BMC Immunol (2008) 9, 72.

Wiesner, M., Zentz, C., Mayr, C., Wimmer, R., Hammerschmidt, W., Zeidler, R., Moosmann, A., Conditional immortalization of human B cells by CD40 ligation. PLoS ONE (2008) 3, e1464.

Willimsky, G., Czeh, M., Loddenkemper, C., Gellermann, J., Schmidt, K., Wust, P., Stein, H., Blankenstein, T., Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness. J Exp Med (2008) 205, 1687.

Witter, K., Mautner, J., Volgger, A., Zahn, R., Kauke, T., A novel HLA-DRB1 allele, HLA-DRB1*0465, was identified in a Hodgkin's lymphoma cell line. Tissue Antigens (2008) 71, 257.

Zwiorek, K., Bourquin, C., Battiany, J., Winter, G., Endres, S., Hartmann, G., Coester, C., Delivery by cationic gelatin nanoparticles strongly increases the immunostimulatory effects of CpG oligonucleotides. Pharm Res (2008) 25, 551.

2009

Alexander, T., Thiel, A., Rosen, O., Massenkeil, G., Sattler, A., Kohler, S., Mei, H., Radtke, H., Gromnica-Ihle, E., Burmester, G. R., Arnold, R., Radbruch, A., Hiepe, F., Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system. Blood (2009) 113, 214.

Babel, N., Brestrich, G., Gondek, L. P., Sattler, A., Wlodarski, M. W., Poliak, N., Bethke, N., Thiel, A., Hammer, M. H., Reinke, P., Maciejewski, J. P., Clonotype analysis of cytomegalovirus-specific cytotoxic T lymphocytes. J Am Soc Nephrol (2009) 20, 344.

Conrad, C., Niess, H., Huss, R., Huber, S., von Luettichau, I., Nelson, P. J., Ott, H. C., Jauch, K. W., Bruns, C. J., Multipotent mesenchymal stem cells acquire a lymphendothelial phenotype and enhance lymphatic regeneration in vivo. Circulation (2009) 119, 281.

Djafarzadeh, R., Milani, V., Rieth, N., von Luettichau, I., Skrablin, P. S., Hofstetter, M., Noessner, E., Nelson, P. J., TIMP-1-GPI in combination with hyperthermic treatment of melanoma increases sensitivity to FAS-mediated apoptosis. Cancer Immunol Immunother (2009) 58, 361.

Ebelt, K., Babaryka, G., Frankenberger, B., Stief, C. G., Eisenmenger, W., Kirchner, T., Schendel, D. J., Noessner, E., Prostate cancer lesions are surrounded by FOXP3(+), PD-1(+) and B7-H1(+) lymphocyte clusters. Eur J Cancer (2009).

Fuchs, H., Gailus-Durner, V., Adler, T., Pimentel, J. A., Becker, L., Bolle, I., Brielmeier, M., Calzada-Wack, J., Dalke, C., Ehrhardt, N., Fasnacht, N., Ferwagner, B., Frischmann, U., Hans, W., Holter, S. M., Holzlwimmer, G., Horsch, M., Javaheri, A., Kallnik, M., Kling, E., Lengger, C., Maier, H., Mossbrugger, I., Morth, C., Naton, B., Noth, U., Pasche, B., Prehn, C., Przemeck, G., Puk, O., Racz, I., Rathkolb, B., Rozman, J., Schable, K., Schreiner, R., Schrewe, A., Sina, C., Steinkamp, R., Thiele, F., Willershauser, M., Zeh, R., Adamski, J., Busch, D. H., Beckers, J., Behrendt, H., Daniel, H., Esposito, I., Favor, J., Graw, J., Heldmaier, G., Hofler, H., Ivandic, B., Katus, H., Klingenspor, M., Klopstock, T., Lengeling, A., Mempel, M., Muller, W., Neschen, S., Ollert, M., Quintanilla-Martinez, L., Rosenstiel, P., Schmidt, J., Schreiber, S., Schughart, K., Schulz, H., Wolf, E., Wurst, W., Zimmer, A., Hrabe de Angelis, M., The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models. Curr Pharm Biotechnol (2009) 10, 236.

Gailus-Durner, V., Fuchs, H., Adler, T., Aguilar Pimentel, A., Becker, L., Bolle, I., Calzada-Wack, J., Dalke, C., Ehrhardt, N., Ferwagner, B., Hans, W., Holter, S. M., Holzlwimmer, G., Horsch, M., Javaheri, A., Kallnik, M., Kling, E., Lengger, C., Morth, C., Mossbrugger, I., Naton, B., Prehn, C., Puk, O., Rathkolb, B., Rozman, J., Schrewe, A., Thiele, F., Adamski, J., Aigner, B., Behrendt, H., Busch, D. H., Favor, J., Graw, J., Heldmaier, G., Ivandic, B., Katus, H., Klingenspor, M., Elisabeth Kremmer, T. K., Ollert, M., Quintanilla-Martinez, L., Schulz, H., Wolf, E., Wurst, W., de Angelis, M. H., Systemic first-line phenotyping. Methods Mol Biol (2009) 530, 463.

Geiger, C., Nossner, E., Frankenberger, B., Falk, C. S., Pohla, H., Schendel, D. J., Harnessing innate and adaptive immunity for adoptive cell therapy of renal cell carcinoma. J Mol Med (2009).

Gross, O., Poeck, H., Bscheider, M., Dostert, C., Hannesschlager, N., Endres, S., Hartmann, G., Tardivel, A., Schweighoffer, E., Tybulewicz, V., Mocsai, A., Tschopp, J., Ruland, J., Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature (2009).

Isensee, J., Meoli, L., Zazzu, V., Nabzdyk, C., Witt, H., Soewarto, D., Effertz, K., Fuchs, H., Gailus-Durner, V., Busch, D., Adler, T., de Angelis, M. H., Irgang, M., Otto, C., Noppinger, P. R., Expression pattern of G protein-coupled receptor 30 in LacZ reporter mice. Endocrinology (2009) 150, 1722.

Kastenmuller, W., Gasteiger, G., Stross, L., Busch, D. H., Drexler, I., Cutting edge: mucosal application of a lyophilized viral vector vaccine confers systemic and protective immunity toward intracellular pathogens. J Immunol (2009) 182, 2573.

Kelly, G. L., Long, H. M., Stylianou, J., Thomas, W. A., Leese, A., Bell, A. I., Bornkamm, G. W., Mautner, J., Rickinson, A. B., Rowe, M., An Epstein-Barr virus anti-apoptotic protein constitutively expressed in transformed cells and implicated in burkitt lymphomagenesis: the Wp/BHRF1 link. PLoS Pathog (2009) 5, e1000341.

Klibi, J., Niki, T., Riedel, A., Pioche-Durieu, C., Souquere, S., Rubinstein, E., Moulec, S. L., Guigay, J., Hirashima, M., Guemira, F., Adhikary, D., Mautner, J., Busson, P., Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells. Blood (2009) 113, 1957.

Kohler, S., Thiel, A., Life after the thymus: CD31+ and CD31- human naive CD4+ T-cell subsets. Blood (2009) 113, 769.

Kumar, D., Hosse, J., von Toerne, C., Noessner, E., Nelson, P. J., JNK MAPK pathway regulates constitutive transcription of CCL5 by human NK cells through SP1. J Immunol (2009) 182, 1011.

Landmeier, S., Altvater, B., Pscherer, S., Juergens, H., Varnholt, L., Hansmeier, A., Bollard, C. M., Moosmann, A., Bisping, G., Rossig, C., Activated human gammadelta T cells as stimulators of specific CD8+ T-cell responses to subdominant Epstein Barr virus epitopes: potential for immunotherapy of cancer. J Immunother (2009) 32, 310.

Markoullis, K., Bulian, D., Holzlwimmer, G., Quintanilla-Martinez, L., Heiliger, K. J., Zitzelsberger, H., Scherb, H., Mysliwietz, J., Uphoff, C. C., Drexler, H. G., Adler, T., Busch, D. H., Schmidt, J., Mahabir, E., Mycoplasma contamination of murine embryonic stem cells affects cell parameters, germline transmission and chimeric progeny. Transgenic Res (2009) 18, 71.

Neuhierl, B., Feederle, R., Adhikary, D., Hub, B., Geletneky, K., Mautner, J., Delecluse, H. J., Primary B-cell infection with a deltaBALF4 Epstein-Barr virus comes to a halt in the endosomal compartment yet still elicits a potent CD4-positive cytotoxic T-cell response. J Virol (2009) 83, 4616.

Nickel, P., Bold, G., Presber, F., Biti, D., Babel, N., Kreutzer, S., Pratschke, J., Schonemann, C., Kern, F., Volk, H. D., Reinke, P., High levels of CMV-IE-1-specific memory T cells are associated with less alloimmunity and improved renal allograft function. Transpl Immunol (2009) 20, 238.

Pandya, M. J., Bendz, H., Manzenrieder, F., Noessner, E., Kessler, H., Buchner, J., Issels, R. D., Interaction of human heat shock protein 70 with tumor-associated peptides. Biol Chem (2009) 390, 305.

Raffetseder, U., Rauen, T., Djudjaj, S., Kretzler, M., En-Nia, A., Tacke, F., Zimmermann, H. W., Nelson, P. J., Frye, B. C., Floege, J., Stefanidis, I., Weber, C., Mertens, P. R., Differential regulation of chemokine CCL5 expression in monocytes/macrophages and renal cells by Y-box protein-1. Kidney Int (2009) 75, 185.

Sattler, A., Wagner, U., Rossol, M., Sieper, J., Wu, P., Krause, A., Schmidt, W. A., Radmer, S., Kohler, S., Romagnani, C., Thiel, A., Cytokine-induced human IFN-gamma-secreting effector-memory Th cells in chronic autoimmune inflammation. Blood (2009) 113, 1948.

Schnurr, M., Orban, M., Robson, N. C., Shin, A., Braley, H., Airey, D., Cebon, J., Maraskovsky, E., Endres, S., ISCOMATRIX adjuvant induces efficient cross-presentation of tumor antigen by dendritic cells via rapid cytosolic antigen delivery and processing via tripeptidyl peptidase II. J Immunol (2009) 182, 1253.

Stumpf, A. N., Schmidt, C., Hiddemann, W., Gerbitz, A., High serum concentrations of cyclosporin related to administration of tigecycline. Eur J Clin Pharmacol (2009) 65, 101.

Uckert, W., Schumacher, T. N., TCR transgenes and transgene cassettes for TCR gene therapy: status in 2008. Cancer Immunol Immunother (2009) 58, 809.

Vertuani, S., Triulzi, C., Roos, A. K., Charo, J., Norell, H., Lemonnier, F., Pisa, P., Seliger, B., Kiessling, R., HER-2/neu mediated down-regulation of MHC class I antigen processing prevents CTL-mediated tumor recognition upon DNA vaccination in HLA-A2 transgenic mice. Cancer Immunol Immunother (2009) 58, 653.

Wolf, S. A., Steiner, B., Akpinarli, A., Kammertoens, T., Nassenstein, C., Braun, A., Blankenstein, T., Kempermann, G., CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis. J Immunol (2009) 182, 3979.

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